Name: Hampton Inn Sikeston
Price range: $107 total
Rating: 8.8

Your Mississippi County Vacation

Book a vacation package to Mississippi County and make planning your adventure easy. With all the logistics arranged before you depart, you can focus on enjoying every minute in this exciting destination. A trip to Mississippi County promises plenty to see and do. Not sure where to start? Charleston is one of the most popular cities to stay here. Stop dreaming and start packing, because your Mississippi County vacation is only clicks away with Expedia.

Find the Best Mississippi County Vacation Packages

Mississippi County Essential Information

Language	English
Currency	U.S dollars
Closest Airport	Nashville Intl. Airport (BNA)

Mississippi County Hotel Deals

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

Fully refundableReserve now, pay when you stay

$62 nightly

$69 total

Feb 3 - Feb 4

Total with taxes and fees

6.6/10 (621 reviews)

Affordable for a quick one night stay. Restaurant and gas station next to hotel.

Reviewed on Jan 20, 2026

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

Fully refundableReserve now, pay when you stay

$90 nightly

$103 total

Feb 8 - Feb 9

Total with taxes and fees

9.4/10 Exceptional! (1,002 reviews)

Clean room and shower, ruffled hotel toilet paper, dinner buffet, breakfast buffet, hot tub and pool. And pets are welcome. Great service and great value.

Reviewed on Feb 1, 2026

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

Fully refundableReserve now, pay when you stay

$94 nightly

$107 total

Feb 8 - Feb 9

Total with taxes and fees

8.8/10 Excellent! (472 reviews)

Great place for an overnight stay. I will be back!

Reviewed on Jan 26, 2026

See all 102 properties in Mississippi County

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.