Mississippi County Vacations & Trips from $290
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Your Mississippi County Vacation
Book a vacation package to Mississippi County and make planning your adventure easy. With all the logistics arranged before you depart, you can focus on enjoying every minute in this exciting destination. A trip to Mississippi County promises plenty to see and do. Not sure where to start? Charleston is one of the most popular cities to stay here. Stop dreaming and start packing, because your Mississippi County vacation is only clicks away with Expedia.
Top destinations in Mississippi County
Charleston
East Prairie
The Latest Mississippi County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Clarion Pointe Hopkinsville near The Bruce Convention Center
Price was $303, price is now $290 per person
$290
per person
Jun 27 - Jun 29
found 1 day ago
Roundtrip flight included
New York (JFK) to Paducah (PAH)
7.4/10 Good! (669 reviews)
Staff was super friendly and always helped with anything that I needed. Felt very safe and welcomed.
Reviewed on May 14, 2026
Holiday Inn Express Fort Campbell-Oak Grove by IHG
Price was $378, price is now $368 per person
$368
per person
Jun 27 - Jun 29
found 1 day ago
Roundtrip flight included
New York (JFK) to Paducah (PAH)
8.8/10 Excellent! (643 reviews)
We arrived late, and left early but was pleased with our room for the small amount of time we were there.
Reviewed on May 25, 2026
Find the Best Mississippi County Vacation Packages
Mississippi County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Nashville Intl. Airport (BNA) |
Mississippi County Hotel Deals
Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $68 total per night from Jun 8 to Jun 9
$68 total
Jun 8 - Jun 9
Total with taxes and fees
6.6/10 (635 reviews)
"Windows were taped over. Hall and linens smelled dusty. No glaaes, cups or coffee pot or coffee."
Reviewed on May 24, 2026
The Riverstone Hotel Charleston-Sikeston
102 Drake St Charleston MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $78 total per night from May 29 to May 30
$78 total
May 29 - May 30
Total with taxes and fees
6.8/10 (412 reviews)
"Coffee"
Reviewed on Apr 22, 2026
Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$111 nightly
The price is $128 total per night from May 31 to Jun 1
$128 total
May 31 - Jun 1
Total with taxes and fees
9.6/10 Exceptional! (1,005 reviews)
"Very nice clean room. Staff was very nice."
Reviewed on May 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
